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Frequently adopted cost-effectiveness thresholds, particularly those recommended by the WHO, fail to acknowledge that programmes and interventions are only cost-effective if their health benefit exceeds that which will be lost because the resources required will not be available to implement other effective interventions. Consequently current judgements about which interventions and programmes are cost-effective do not reflect the reality of resource constraints and their use is likely to reduce overall population health and exacerbate healthcare inequalities. Thresholds based upon assessments of how else resources can be used hold promise of generating greater population health gains from the means available.  In this research paper from […]

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About Lablite

Lablite is an implementation project investigating strategies to roll out HIV treatment safely and cost-effectively in real-life settings in sub-Saharan Africa. The project is working closely with ministries of Health in 3 countries in Africa (Malawi, Zimbabwe and Uganda), and has the overall aim of evaluating rolling-out of antiretroviral therapy (ART) to smaller health centres, nearer to where people live, using a clinically-driven monitoring approach. It aims to inform national and international policy on how best to use the limited funds available to increase coverage of HIV treatment.

Lablite involves:

  • A situation analysis to map what is happening on the ground
  • A demonstration project to show how decentralised delivery of HIV treatment would work in lower level health centres with little or no laboratory facilities
  • Health economics and modelling work to assess the economic consequences of different HIV programmes

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MRC Clinical Trials Unit at UCL,
Aviation House, 125 Kingsway
Postcode: WC2B 6NH